Actor Diganth Manchale describes Powder as a comedy extravaganza, where he collaborates with actresses Dhanya Ramkumar and Sharmiela Mandre, along with comedy stalwarts Rangayana Raghu, Nagabhushana, Ravishankar Gowda, Gopalkrishna Deshapande, and Anirudh Acharya. Diganth praises the ensemble cast as a major strength of the film, highlighting their dedication to enhancing every scene for perfect comic timing. Director Janardhan Chikkanna's skill in managing nine characters with their own storylines is also commended. Sharmiela Mandre plays a fierce assassin with intense action sequences that required rigorous training. Dhanya Ramkumar portrays a small-town girl named Nithya, who finds Powder a refreshing and light-hearted movie amidst the current trend of darker films. She initially doubted her comedic timing but received encouragement and guidance from Janardhan to deliver a memorable performance.